Stefan D. Holubar

MD, MS, FACS, FASCRS

Colorectal Surgery·IBD Surgery·Surgical Outcomes

Areas of Expertise

IBD Surgery
Ileal pouch-anal anastomosis, restorative proctocolectomy, and minimally invasive approaches for ulcerative colitis and Crohn's disease.
Colorectal Oncology
Surgical strategy, risk stratification, and outcomes analysis for colorectal and anal malignancy.
Surgical Outcomes Research
NSQIP-based analyses, risk-adjustment modeling, quality benchmarking, and multivariate statistical methodology.
Clinical Trial Design
Protocol development, endpoint selection, biostatistical planning, and IRB navigation for surgical and device trials.
Expert Opinion
Independent expert review for medicolegal, regulatory, and health technology assessment matters in colorectal and IBD surgery.
Quality Improvement
Collaborative quality programs, SSI reduction, VTE prophylaxis protocols, and perioperative process redesign.
Artificial Intelligence
Clinical AI tool development, large-language model applications, risk calculators, and AI-powered patient education platforms for surgical and IBD care.
Digital Health Platforms
Design and development of clinical web platforms, patient education sites, provider portals, and AI-backed literature interfaces for surgical subspecialties.

Biography

Stefan D. Holubar, MD, MS, FACS, FASCRS

Dr. Stefan Holubar is a Professor of Surgery and colorectal surgeon specializing in IBD surgery and surgical outcomes research. He received his MD from the University of Vermont in 2002, completed General Surgery training at North Shore–LIJ, earned a Master of Science in Clinical and Translational Research, and completed Colorectal Surgery fellowship at Mayo Clinic Rochester (2007–2010). He subsequently served as Chief of the Division of Colon and Rectal Surgery at Dartmouth-Hitchcock Medical Center before joining a major academic medical center in 2017, where he has led IBD Surgery and research programs.

Nationally, Dr. Holubar co-leads the ACS NSQIP IBD Collaborative and has served as Chair of the American Society of Colon and Rectal Surgeons (ASCRS) IBD Committee (2023–2025). He is Principal Investigator of the Crohn's & Colitis Foundation's longitudinal surgical cohort, IBD-SIRCQ. With over 300 peer-reviewed publications and 225+ focused on IBD, he is among the most productive surgical IBD researchers in North America.

Dr. Holubar's clinical and research focus is surgery for IBD and artificial intelligence, with special interest in redo IPAA and perianal Crohn's disease. Recent contributions include Twisted Pouch Syndrome, the Pouch Tortuosity Index, the Mesenteric Excision and Exclusion procedure, and 3D Pouchography. He has developed multiple clinical AI platforms including IBDology.org, Pouchy.org, Pouchology.org, and founded the iPouch Consortium.

300+ peer-reviewed publications
225+ IBD-focused articles
20+ book chapters
1 co-edited textbook
Professor of Surgery
ASCRS IBD Committee Chair

Consulting Inquiries

For consulting engagements, expert opinion requests, speaking invitations, or research collaboration — please reach out directly.